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Etta James has died, according to her longtime friend and manager, Lupe De Leon. She was 73 and had been diagnosed with leukemia in 2010. James, who also suffered from dementia and hepatitis C, died at a hospital in Riverside, California.

James was recently released from the hospital just days after her condition improved enough for her to be removed from a breathing machine.

This is a tremendous loss for the family, her friends and fans around the world,” De Leon said. “She was a true original who could sing it all – her music defied category. I worked with Etta for over 30 years. She was my friend and I will miss her always.”

Condolences goes out to her family.

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Etta James Terminally Ill

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